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Home » Browse All Summaries » The Anti-Aging Solution by Vincent Giampapa, M.D, Ronald Pero, Ph.D. and Marcia Zimmerman, C.N.
The Anti-Aging Solution: 5 Simple Steps to Looking and Feeling Young
By Vincent Giampapa, M.D, Ronald Pero, Ph.D. and Marcia Zimmerman, C.N.
Summarized with permission of Wiley (www.wiley.com). All rights reserved.
Step 4: Supplement You Genes
The power of healing foods comes from their broad-based ability to prevent disease by nutritionally fortifying the biochemical processes that have been naturally selected by evolution to protect us from disease and aging. However, even with a dramatic change in diet, supplements containing concentrated forms of nutrients, usually from food sources, are needed to overcome the damaging effects of micronutrient deficiencies, pollution, radiation, and internally generated free radicals. Since vitamins and minerals are required to cofactor metabolic enzymes, micronutrient deficiencies can cause profound alterations in normal cellular function. Nutraceutical supplements can also speed up DNA repair capability, the bottom line in preventing most diseases by reducing DNA damage.
Benefits of Carotenoids
- Xanthophyll carotenoids, vitamins C and E can delay onset of macular degeneration and cataracts.
- Astaxanthin, canthaxantin, and beta-carotene have anti-cancer activity.
- High levels of carotenoids from supplements reduce oxidative damage to DNA.
- Carotenoids protect against free radicals.
- Astaxanthin and lycopene are more protective against UV radiation than beta-carotene.
- High serum levels of lycopene may play a role in the early prevention of atherosclerosis.
- Supplemental beta-cryptoxanthin and zinc reduce the risk of rheumatoid arthritis.
- Curcumin from turmeric scavenges nitric oxide, thus reducing inflammation and protecting against cancer.
Daily Prescription for Carotenoid Supplementation
Key: milligrams = mg, micrograms = meg, international units = IU
| Mixed natural carotenoids |
5,000 to 10,000 IU of vitamin A activity from Daniella salina |
| Lycopene |
2 to 5 mg from tomato seed extract |
| Lutein and zeaxanthin |
2 to 5 mg from extract of marigold flowers |
| Turmeric rhizome (Curcuma longa) 95 percent extract |
100 mg |
| Astaxanthin, algal source |
1 to 10 mg |
Benefits of Vitamin E and Tocotrienols:
- Lowers LDL cholesterol oxidation
- Reduces the risk of stroke by protecting LDL cholesterol
- Lowers the risk of heart disease
- Improves insulin action in healthy older individuals and those with diabetes
- Raises levels of glutathione another antioxidant and detoxifying agent in diabetic patients
- Protects against exercise-induced oxidative damage
- Slows the development of cataracts
- Reduces inflammation and enhances immune response
- Reduces cognitive decline in aging
Tocotrinols have anti-aging therapeutic activity beyond that of vitamin E. In fact, gamma-tocotrienol is the most potent cholesterol-lowering member of the entire E family. Recent studies have shown that tocotrienols lower a number of lipid-related risk factors, including total cholesterol, LDL, apolipoprotein B, and lipoprotein A (gamma-tocotrienol 200 mg per day lowered cholesterol 31 percent), suppress inflammatory agents such as thromboxane B2 and platelet factor 4, reduce blood levels of lipid peroxides, induce apoptosis and inhibit tumor growth in human breast cancer cells.
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