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Home » Browse All Summaries » The Anti-Aging Solution by Vincent Giampapa, M.D, Ronald Pero, Ph.D. and Marcia Zimmerman, C.N.

The Anti-Aging Solution: 5 Simple Steps to Looking and Feeling Young

By Vincent Giampapa, M.D, Ronald Pero, Ph.D. and Marcia Zimmerman, C.N.

Summarized with permission of Wiley (www.wiley.com). All rights reserved.

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Step 2: Nourish your Genes

Sugars perform vital functions in the body in addition to providing the major source of energy as glucose. Complex sugars cover the exposed surface of membrane receptors, flagging down passing vitamins and chemicals. Other sugars such as Glucosamine protect joints. These functional sugars can be damaged by oxidative stress caused by free radicals, leading to crippling conditions such as osteoarthritis. Oxidized glucose coating the surface of proteins such as collagen, hemoglobin and albumin prevents them from functioning. Scientists call this process glycation. Collagen is the most plentiful protein in your body and the one most affected by glycation. Skin, blood, and lymph vessels, joints, tendons, ligaments, and internal organs are comprised of collagen.

Most aging conditions are linked to glycation including:

  • Memory loss due to sugar coating of brain neurons (brain cells)
  • Clinical depression due to disruption of neurotransmitter function
  • Reduced stress adaptation due to damaged Cortisol receptors
  • Hormone imbalances due to increased unbound or free Cortisol
  • Skin wrinkling and sagging due to collagen glycation
  • Impaired immune function due to damage to thymus gland, lymphatic tissue, and immune cells
  • Allergies, leaky gut syndrome, and irritable bowel disorders due to impaired gastrointestinal function
  • Persistent sleepiness after meals, teen-age blemishes and middle-aged wrinkles are the first signs that sugar problems exist due to eating meals high in carbohydrates, especially white flour products.

Glycation is a progressive process in which destructive byproducts called advanced glycation end products (AGEs) are formed. AGEs cause many aging conditions.

Dietary Antioxidants Work Together to Counteract Oxidative Stress

Without the entire complement of antioxidants, all free radicals are not neutralized, and are accumulated in the body. We need antioxidants such as: Vitamin C, Bioflavonoids, Tocopherols, Tocrienols, and Carotenoids.

Foods to Protect Genes

Colors: yellow, orange, bright red, yellow/green

Phytonutrients: carotenes: alpha-carotene, beta-carotene, lycopene, lutein, zeaxanthin, vitamin C (in some)

Serving size: 1 half cup cooked vegetables or cut-up fruit Servings per day: 2-3
Vegetables Fruit Spices
Carrots Apricots Allspice
Corn Avocados Cardamom
Grape leaves Bananas Cayenne
Green beans Cantaloupes Cinnamon
Hot peppers, cayenne Grapefruits Cloves
Lettuce Kiwi Curry
Peas Lemons Ginger
Pumpkin Mangos Nutmeg
Spinach Nectarines Saffron
Summer squash Oranges, pears Turmeric
Sweet peppers Papaya  
Tomatoes, turnips Passion fruit  

Foods in the yellow/orange/red category are exceptional antioxidants, and are the first line of defense against free radicals generated from physiological stress, air pollution, tobacco smoke and chemical and ultraviolet exposure. As membrane antioxidants they protect the cell and its organelles, retain membrane fluidity, and improve intercellular communication. They move throughout the body, on very low-density (VLDL), low-density (LDL), and high-density (HDL) lipoproteins. There they are able to prevent oxidation of lipoproteins, a major factor in atherogenesis.

Carotenes have also been found to reduce angina. Three carotenes: alpha, beta, and gamma can be converted into vitamin A. Carotenes are:

  • photoprotective
  • anti-inflammatory
  • cell growth and immune modulators
  • anti-arcinogenic
  • protective of the brain and nervous system.

Winter vegetables such as squash, yams, sweet potatoes and pumpkin are high in carotenoid antioxidants and give you extra protection during cold and flu season. Winter antioxidant fruits and vegetables exposed to frost are sweeter and contain higher levels of phytonutrients that protect against environmental stress. Spices high in carotenoids have the characteristic golden color, are very flavorful, and help you digest your food and speed up a sluggish metabolism. Instead of salt, use pepper and spices liberally, especially when eating protein and foods high in oil content. You need at least three different carotenoid foods every day to preserve your youthfulness.
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